Thermo Fisher Scientific

Thermo Scientific™ MAS™ Omni•Infectious™ Quality Controls are the first in a line of serological QC products we are continuing to develop to support the monitoring of in vitro diagnostic assays.  These new controls for viral and bacterial pathogens allows for optimization of daily workflow and increased productivity. They are true third-party positive and negative controls for hepatitis, HIV, HIV p24, Syphilis and HTLV

These human serum base products are ready-to-use directly from storage and offer  minimum of 30-day open vial stability when stored at 2 to 8° C.  As with all Thermo Scientific MAS Quality Controls, the MAS Omni•Infectious Quality Controls are consolidated, and users can efficiently monitor assay performance, streamline operations and potentially reduce spending without sacrificing quality or throughput. Furthermore, assessment of your serological assay performance can be completed in an objective and unbiased manner using a third-party control.

The proven Thermo Scientific Orbitrap technology in the Thermo Scientific Orbitrap Exploris 120 mass spectrometer accelerates your route to qualitative and quantitative confidence for both method development and everyday testing purposes. With its unique ability to provide consistently accurate data and a design made for operational simplicity, it sets the new standard in instrument productivity and ruggedness. Key benefits of Orbitrap Exploris 120 Mass Spectrometer include:

1. Confidently, perform high-throughput qualitative and quantitative analysis
2. Keep your laboratory running seamlessly with the new standard in instrument ruggedness
3. Focus on driving results with faster method set-up

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Deliver on your objectives with the Thermo Scientific Orbitrap Exploris 240 mass spectrometer by combining application flexibility with the performance to drive discovery and identification, plus receive the quantitative precision and accuracy you need to confidently scale up and achieve impact. With operational simplicity through intelligent data acquisition and processing, discover your fast track to confident results regardless of sample complexity, the depth of insights required or the presence of unknown compounds. Key features include: 1. Everyday experimental flexibility 2. Faster path to confident insights 3. Reliable, robust, and maintainable 4. Focus on driving results with faster setup

Automated clinical analyzer combining sample preparation, liquid-chromatography and mass spectrometry. The Cascadion SM Clinical Analyzer and the assays included in this system are for in vitro diagnostic use in clinical laboratories. The functionality and features include:

• Random Access: continuous, random loading of patient samples without interruption
• Bi-directional host-query LIS interface: automated order processing and results reporting
• Walkaway Operation: seamless transfer between all operation steps without intervention
• Multi-analyte Processing: multiple tests can be run from a single sample within an assay
• Intuitive Graphical User Interface: select local languages available
• Closed system: all components needed available through Thermo Fisher Scientific

The Cascadion SM 25-OH Vitamin D Assay in a ready to use kit includes the following features:

• Standardized to NIST reference material
• Aligned to CDC reference method
• 30-day calibration stability

Thermo Fisher Scientific products are distributed globally so uses, applications, and availability of product in each country depend on local regulatory authorization status.

Day after day, analytical testing laboratories face considerable challenges due to backlogs of time-critical samples, rising per-sample costs, availability of skilled laboratory technicians, and chromatography maintenance or downtime. The Thermo Scientific™ VeriSpray™ PaperSpray ion source uniquely addresses these concerns. Combine the VeriSpray ion source with next-generation Thermo Scientific™ mass spectrometers to reduce time to results and cost per test with automated, high-throughput, direct mass spectrometry (MS)-based sample analysis. The VeriSpray ion source allows use of “dilute and shoot” methods to minimize solvent consumption and time-consuming sample preparation steps like derivatization, while avoiding needs for expert operators. For laboratories currently performing LC or GC methods, or for those that want to add the robust sensitivity and selectivity of MS-based tests, the VeriSpray ion source provides an ideal alternative to the complexity of chromatography-based solutions. ​

PCT: an aid for risk assessment in COVID-19 secondary bacterial infections
B·R·A·H·M·S PCT (Procalcitonin) is widely used to assess the risk of bacterial infection and progression to severe bacterial sepsis and septic shock in conjunction with other laboratory findings and clinical assessment. Further, the change of PCT over time is used to determine the mortality risk in patients with bacterial sepsis.

In patients with suspected or confirmed lower respiratory tract infections (LRTI), including community acquired pneumonia (CAP), acute bronchitis and acute exacerbations of COPD (AECOPD), PCT is an aid in decision making on antibiotic therapy for inpatients or patients presenting in the emergency department (ED).

Procalcitonin has now been shown, in evolving descriptive studies, to be an additional valuable tool in the current COVID-19 pandemic to early identify patients at low risk for bacterial coinfection and adverse outcome.[1-6,17] Learn more: thermofisher.com/pct-covid-19.

Complete workflow enabling clinical laboratories to evaluate 94 specimens in under 3 hours, or 382 specimens in under 6.5 hours, with a single Thermo Scientific™ KingFisher™ purification system and Applied Biosystems™ real-time PCR system combination.
Targeted specificity to 100% of currently available complete genomes for SARS-CoV-2.

Assays target spike (S) protein and nucleocapsid (N) protein regions having higher specificity and exhibiting lower risk for mutation.

Applied Biosystems™ COVID-19 Interpretive Software, which automatically converts genetic analysis data into diagnosis, helping reduce risk of user interpretation error.

Six approved specimen types, requiring only 200 to 400 μL of sample: bronchoalveolar lavage (BAL), mid-turbinate swabs, nasal swabs, nasopharyngeal swabs, nasopharyngeal aspirate (nasal aspirate), and oropharyngeal swabs.

The Applied Biosystems™ TaqPath™ COVID-19 CE-IVD RT-PCR kit has obtained CE-IVD marking and the TaqPath COVID-19 Combo Kit has obtained EUA marking.

The TaqPath COVID-19, Flu A, Flu B Combo Kit is available in a single 1,000 reaction-size kit for maximum throughput. Features include:

• Single test for SARS-CoV-2, influenza A, and influenza B—detect and differentiate between disease states with similar clinical symptoms and get the information needed to help monitor the spread of COVID-19 and the flu
• Affordable and scalable—add to your existing COVID-19 testing menu and infrastructure to expand your respiratory sample testing while maintaining low operational costs and workflow simplicity
• Sensitive and specific—get 100% homology to >99.9% of known SARS-CoV-2 genomes and robust performance for detecting flu A and B strains, providing increased confidence in results
• Complete solution for clinical labs—Applied Biosystems Pathogen Interpretive Software automatically converts genetic analysis data into a readable report, helping reduce risk of user interpretation error