The Jackson Laboratory  

Bar Harbor,  ME 
United States
http://www.jax.org/
  • Booth: 940

 Products

  • JAX Humanized Mice Solutions

    Humanized CD34+ mice (hu-CD34) are a robust in vivo platform for analyzing the safety and effectiveness of potential new drugs to modulate the immune system. Hu-CD34+ mice are advantageous in vivo models for long-term studies in the fields of human immune cell biology, immuno-oncology, and infectious disease.

    Models engrafted with cord blood-derived hematopoietic stem cells (HSC) develop multi-lineage engraftment and display robust T-cell maturation and T-cell dependent inflammatory responses. In addition, an improved human myeloid and NK lineage development is demonstrated in humanized NSG™-SGM3 and NSG™-Tg(IL15) mice. Large cohorts of humanized CD34+ NSG™, NSG™-SGM3 and NSG™-Tg(IL15) mice are available for immediate delivery or to enroll in JAX drug efficacy testing services.

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  • JAX Models Services for Autoimmune Diseases

    Efficacy Studies Accelerating Drug Discovery

    We offer customizable study designs, to test the effectiveness of novel or existing therapeutic compounds using well published mouse models for the following autoimmune diseases:

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  • JAX Models and Services for Infectious Disease
    We have the capability to provide large cohort of humanized NSG™ mice readily available for researchers and drug discovery scientists.  Humanized mouse models are powerful tools to study viral host-pathogen interactions, and to accelerate the development of novel therapies for human immunodeficiency virus (HIV) as well as other viral diseases with high morbidity and mortality including Dengue and Epstein-Barr virus which only infect human cells....

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