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Oncomine™ Tumor Mutation Load Assay
The new Ion Torrent Oncomine Tumor Mutational Load Assay is a next-generation sequencing (NGS) assay that enables accurate quantification of somatic mutation counts to assess tumor mutation burden (TMB) from FFPE samples within 2.5 days. The solution includes automated library preparation and a report linked to relevant labels and clinical trials.... More Info Less Info
       


Immune checkpoint inhibitors have changed the treatment paradigm for a variety of cancers, but not all patients will respond to these drugs. Given the complexity of the immune response and tumor biology, additional biomarkers are needed to evaluate the response of samples to immunotherapies. Tumor mutation burden (TMB) is an exciting biomarker that may have the potential to accurately stratify patient samples in the future. The new Ion Torrent Oncomine Tumor Mutational Load Assay is a next-generation sequencing (NGS) assay that enables accurate quantification of somatic mutation counts to assess TMB from FFPE samples in 2.5 days. The solution includes automated library preparation and a report linked to relevant labels and clinical trials.

Oncomine™ Pan-Cancer Cell-Free Assay
The new Ion Torrent Oncomine™ Pan-Cancer Cell-Free Assay is a multibiomarker next-generation sequencing (NGS) assay that enables detection of relevant mutations, CNVs and fusions from a single tube of blood, down to 0.1% frequency. Labs generate reports with labels, guidelines and clinical trials within 3 days from a single liquid biopsy sample.... More Info Less Info
     


By enabling a noninvasive and cost-effective alternative to traditional tissue biopsies, liquid biopsy may redefine the future of cancer care. The new Ion Torrent Oncomine™ Pan-Cancer Cell-Free Assay is a multibiomarker next-generation sequencing (NGS) assay that enables detection of SNPs, indels, CNVs and fusions from a single tube of blood, down to a level of 0.1% in genes relevant to solid tumors. Investigate tumor heterogeneity and reoccurrence from a 10 mL liquid biopsy sample with accurate and repeatable results and generate a report with labels, guidelines and clinical trials within 3 days.

Oncomine™ Childhood Cancer Research Assay
The Ion Torrent Oncomine Childhood Cancer Research Assay is a next-generation sequencing (NGS) assay for comprehensive genomic profiling of cancers affecting children and young adults. Analyze >1400 fusion drivers, gene expression markers, CNVs and somatic mutations from blood, bone marrow or FFPE tissue samples and generate results within 3 days.... More Info Less Info
     


​The types and driving genetic aberrations of childhood and pediatric malignancies are different than those affecting the adult population, so a specifically designed panel is needed to advance clinical research for these cancers. The Ion Torrent Oncomine Childhood Cancer Research Assay is a unique, next-generation sequencing (NGS)-based tool designed for comprehensive genomic profiling of cancers affecting children and young adults. Analyze >1400 fusion drivers, gene expression markers, CNVs and somatic mutations  from blood, bone marrow or FFPE tissue samples and generate results in 2 to 3 days. Every user also gets free membership in the International Childhood Cancer Network (ICON) to collaborate with experts in the field.

Oncomine™ Myeloid Research Assay
The new Ion Torrent Oncomine Myeloid Research Assay is a next-generation sequencing (NGS) assay that interrogates relevant DNA mutations and fusion transcripts associated with myeloid disorders in a 2-day workflow. Solution includes automated library preparation and reporting solution that links variants to labels, guidelines and clinical trials.... More Info Less Info
     


​Current methods for the analysis of hematological malignancies often involve multiple sequential tests and laborious workflows. Adoption of next-generation sequencing (NGS) into clinical research laboratories has created an unprecedented opportunity to profile the multiple relevant driver genes in myeloid malignancies in a single test. The new Ion Torrent Oncomine Myeloid Research Assay is a comprehensive, targeted NGS assay that interrogates relevant DNA mutations and fusion transcripts associated with myeloid disorders in a quick and easy NGS run. The workflow also includes automated library preparation and a reporting solution that links relevant variants to labels, guidelines and clinical trials.


Thermo Scientific™ Cascadion™ SM Clinical Analyzer

Fully automated, random access LC-MS/MS analyzer for in vitro diagnostic use. Clinical analyzer with integrated sample preparation, liquid-chromatography and mass spectrometry. Easy-to-use, Thermo Scientific™ Cascadion™ SM Clinical Analyzer and the assays included in this system are for use in routine clinical laboratories. Not FDA 510 (k) cleared.... More Info Less Info
   






A fully automated random access liquid-chromatography-tandem mass spectrometry (LC-MS/MS) analyzer. Up to 60 samples can be loaded at a time, enabling samples to be added as they arrive. Sample racks accommodate different cups and barcoded primary sample tubes to allow testing of serum, plasma and whole blood matrices. After sample processing, the analyzer is designed to produce test results every two minutes.


The Cascadion system is a complete solution with all reagents, supplies from a single supplier. The system offers full traceability: each result can be linked to the specific lots of reagent, calibrators and controls. The analyzer can be connected to Middleware or a LIS for a fully automated workflow. Product not FDA 510 (k) cleared.


Thermo Scientific™ TSQ Altis™Triple Stage Quadrupole
Next-generation triple quadrupole mass spectrometers deliver exceptional performance for the most demanding clinical research applications and routine quantitative workflows. Thermo Scientific™ TSQ Altis™ and TSQ Quantis™ Triple Stage Quadrupole mass spectrometers offer outstanding robustness, extreme sensitivity and speed for demanding assays.... More Info Less Info
     


Clinical research laboratories can now obtain extreme sensitivity, outstanding robustness, and speed with the new Thermo Scientific™ TSQ Altis™ and TSQ Quantis™ Triple Stage Quadrupole mass spectrometers. Next-generation technology such as Active Ion Management (AIM+), segmented quadrupoles, and enhanced dual-mode electron multipliers offer superior performance and reliable routine workflows for nearly all molecule types in complex matrices. Address the most stringent analytical challenges for targeted quantitation with the Thermo Scientific™ TSQ Altis™ Triple Quadrupole MS. The Thermo Scientific™ TSQ Quantis™ Triple Quadrupole MS delivers unprecedented robustness with best-in-class sensitivity for everyday use and for every user.

Thermo Scientific™ ChromaCare + UHPLC-MS Solvents
The new Thermo Scientific ChromaCare reagents are designed to reduce contaminants and prevent protein precipitation. Thermo Scientific UHPLC-MS ultrapure solvents reduce background noise for high-quality chromatograms. Together they are helping to raise the bar in instrument performance and maximize productivity across laboratories.... More Info Less Info
   


ChromaCare was developed for both start-up/ upkeep of LC-MS columns and  chromatographs. The Instrument Flush Solution reduces background noise, facilitating installation and preventative maintenance routines for optimal performance. The Biologics Flush Solution prevents proteins from clogging probes, minimizing instrument downtime and preserving sample integrity. UHPLC-MS solvents help achieve high-quality separation results by enhancing mass sensitivity and resolution, reducing formation of metal ion adducts and improving peak profiles. They enable optimal signal-to-noise ratio while keeping UV-absorbing and MS-ionizing impurities to a minimum, providing baselines with an extremely low level of background interferences, regardless of the detector.

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