BioChain  

Newark,  CA 
United States
http://www.biochain.com
  • Booth: 773

Booth Profile

BioChain primarily focuses on providing high quality biosamples and sample analysis tools for research. Biospecimens include tissue sections, panels, arrays, as well as gDNA, RNA and protein lysate from our tissue bank. We provide a variety of nucleic acid and protein lysate extraction and analysis kits as well as automated nucleic acid extraction equipment. BioChain can perform custom projects - including tissue procurement, custom nucleic acid or protein extractions. Our other focus has been in developing and licensing early cancer diagnostics technologies through liquid biopsy. BioChain Beijing has licensed Septin9 methylation assay for colorectal cancer screening, and received Chinese FDA’s approval. Currently, this assay is used to screen patients in hospitals across China. In our US research facility, we developed and successfully launched our liquid biopsy cfPureTM cell-free DNA extraction kit and currently we are launching our vamPure whole blood DNA extraction kit.


 Press Releases

  • Over 8.2 million people die of cancer worldwide each year, and an estimated 23 million new cases annually will occur worldwide by 2030. This is a reality that has left researchers searching for a simple, safe, and cost effective way to detect cancer in its earliest stages. The new developing field of Liquid Biopsy, which allows scientists to screen for dozens of cancers from a single blood sample, hopes to be that answer. Representing a leap forward in cancer research, BioChain Institute, Inc. and Chief Executive Officer Grace Tian are launching the cfPure MAX Cell Free DNA Extraction Kit, a product designed to extract cell free DNA from plasma samples. “This kit is designed for rapid and efficient purification of circulating cell free DNA,” Tian stated. “The use of our silica-coated paramagnetic bead technology allows researchers to quickly isolate cfDNA from plasma allowing for users to process hundreds of samples a day. To develop an effective liquid biopsy based screening test, thousands of samples must be screened and this kit will expedite that process." Cell free DNA, or cfDNA, is a short fragment of DNA that is released by dying cells (including tumor cells) into body fluids (e.g. blood, urine, cerebrospinal fluid, etc). The importance of cfDNA in liquid biopsy is that it can be analyzed to look for mutations that are associated with cancer. In addition, because cfDNA is found within the body fluids of patients with early stages of certain cancers, BioChain’s product would mean a noninvasive and highly accessible way to detect these cancers. Tian adds, “A small amount of total cfDNA in plasma is circulating tumor DNA, and detecting this small fraction is the key to discovering cancer at its earliest stages when survival rates are high. To detect the small amount of tumor DNA it can take relatively large amounts of plasma. The cfPure Max cfDNA Extraction Kit was optimized and structured to rapidly process these large volume samples.” This kit is intended for research use only. The future in cancer treatment relies on speed and accessibility of detection methods for people regardless of where or how they live -- BioChain’s new kit is a welcome step in the right direction. Further information is available at https://www.biochain.com/product/cfpure-max-cell-free-dna-extraction-kit/.

    About BioChain:   BioChain is the world leader in high quality processed bio-sample products and analysis services used in advancing translational medicine, companion diagnostics, and clinical product research and development. BioChain’s products are available for DNA and RNA sequencing, PCR and RT-PCR, gene expression analysis, liquid biopsy, DNA and RNA purification, protein extraction and purification, and protein expression analysis. BioChain’s One-Stop Services for Next Generation Sequencing, from clinical sample collection, sample preparation, sequencing to bioinformatics analysis, will revolutionize the industry.

  • At 5 liters per average human, blood is one of the most abundant tissues in the body. High quality analysis of blood aids with diagnosis, treatment, and research methods. An important area in the market right now is DNA extraction in which blood is the prime sample. Introducing a revolutionary tool in therapeutic and genomic research, BioChain’s CEO Grace Tian is pleased to launch the vamPure Blood Nucleic Acid Extraction Kit. This highly validated product is designed to get the highest yield of genomic DNA from either fresh or frozen blood samples.

    “This kit is designed for rapid and efficient purification of genomic DNA from blood,” Tian stated. The proprietary silica-coated paramagnetic bead technology allows researchers to obtain higher yields with optimal purity. Having a short and scalable protocol makes processing the sample efficient with minimal waste produced. The chief officer foresees the versatility of the kit being able to adapt to automated systems to the point of allowing researchers to process hundreds of samples per day.

    Obtaining and amplifying genomic DNA from blood allows access to a patient’s genetic profile such as by constructing a genomic library using non-invasive methods. The DNA may then be used for various downstream applications, such as Next Generation Sequencing (NGS), polymerase chain reaction (PCR), and chromosomal copy-number variation (CNV) research methodologies. The DNA obtained from blood is also useful in pharmacogenomics which looks at how one’s genetic makeup can affect drug response in diseased states.

    The future of genetic research and pharmacogenomics requires cost-effective scalable techniques that support automation without sacrificing speed or quality. BioChain’s easy-to-use protocol and competitive yield provide the perfect product.

    This kit is intended for research use only. Further information is available at https://www.biochain.com/product/vampure-blood-nucleic-acid-extraction-kit.

    About BioChain

    BioChain is the world leader in high quality processed bio-sample products and analysis services used in advancing translational medicine, companion diagnostics, and clinical product research and development. BioChain’s products are available for DNA and RNA sequencing, PCR and RT-PCR, gene expression analysis, liquid biopsy, DNA and RNA purification, protein extraction and purification, and protein expression analysis.