Tempe,  AZ 
United States
  • Booth: 1579

Booth Profile

SCIENION provides systems and services for the contact-free printing of single cells, biological and chemical agents for diagnostics, pharmaceutics, veterinary, plant and food analytics. Our dispensers allow for precise spotting in the pico- to micro-liter range on a variety of substrates, from silicon wafers and microtiter plates, to lateral flow strips. We now carry the best colorimetric and fluorescence array scanners. New sciPOLY allows immobilization without surface functionalization

 Press Releases

  • The main challenges associated with cell line development are maintaining high cell viability and ensuring monoclonality of isolated cells. Unlike flow cell sorters, which induce high stress and compromise cell viabilities, automated cloning using cellenONE is a gentle and precise method to achieve unparalled clonal recoveries in both standard (96 MTP) and high density (1536 MTP) substrates. This is demonstrated with CHO cells, one of the most common cell line used in recombinant therapeutic proteins manufacturing.

    The number of wells containing single CHO colonies were counted for each plate (six 96 MTP and one 1536 MTP) and the percent of wells containing single colonies was calculated (Figure 3).

    Outstanding clonal recoveries were observed with 96% and 94% of wells containing single colonies in 96 and 1536 MTP, respectively (Figure 2). Additionally, the remaining wells were empty and did not contain multiple colonies. To our knowledge, this is the first time such high clonal recoveries have been demonstrated with CHO cells in both standard (96 MTP) and very high density (1536 MTP) substrates.

    This experiment demonstrates the cellenONE as an ideal platform for undertaking automated cloning in both standard and high density substrates as it ensures monoclonality while maintaining outstanding clonal recovery.

    Compatibility with high density substrates offers a dramatic increase in throughput to automatically process the equivalent of 16 individual 96 MTP in under an hour leaving personnel free to perform less routine tasks.

    In addition to saving time, one can save on consumables and expensive reagents while ensuring documentation and monoclonality of all isolated cells.

  • This year, SCIENION and cellenion will organize a yearly wkrshop in Lyon, from 3rd to 4th of September.

    The agenda will incude two sessions every day, presenting fully automated testing platforms from sample to results and new technologies

    SESSION 1. Fully Automated Testing Platforms From Sample to Results
    09:00 - 9:30 MOBIDIAG
    Novodiag® Diagnostic Platform
    9:30 - 10:00 Master Diagnostica
    Multiplexing Molecular Diagnostic kits based on DNA-Flow Technology
    10:00 - 10:30 MyCartis
    Antelope Dx: Diagnostics where you need it
    10:30 - 10:45 Break
    10:45 - 11:15 Infynity Biomarkers
    Changing the paradigm of serology testing from single markers to
    multiplex testing: Study model of Chagas disease
    11:15 - 11:45 AXO Science
    105plex for the straightforward characterization of bacteria and resistance

    SESSION 2. New Technologies: Trends for Tomorrow
    13:30 - 14:00 Biopalitra
    Multiplexed immunoassays for biomarkers of HBV, HCV, HIV & Treponema
    14:00 - 14:30 Joanneum Research
    High-throughput Roll-to-Roll Production of Biosensors
    14:30 - 15:00 Nanovation
    Nano-Based Sensors for Respiratory Monitoring: From Lab to Market
    15:00 - 15:15 Break
    15:15 - 15:45 University of Lyon
    3D bioprinting and ink-jet bioprinting hybrid method for tissue engineering
    15:45 - 16:15 Génoscope - Sequencing National Center
    Cell fate decisions implicated on brain complexity

    On the second day, the focus will be single cell isolation and its applications.

    SESSION 3. Unravelling Cancer Genomics at Single Cell Level
    09:00 - 9:30 University of British Columbia Cancer Research Center
    Sequencing the DNA present in single sorted cells
    9:30 - 10:00 German Cancer Research Center (DKFZ)
    Epigenetic regulation in stem cells and cancer
    10:00 - 10:30 Centre Léon Bérard
    Single cell analysis in immuno-oncology : R&D, diagnosis,
    prognosis and much more
    10:30 - 10:45 Break
    10:45 - 11:15 Institute of Cancer Research London
    Isolating single-cell clones to measure cancer heterogeneity
    11:15 - 11:45 Biolidics
    Phenotyping characterization of CTC in cancer using spiral
    microfluidic enrichment
    11:45 - 12:15 Gilupi
    In vivo capturing of CTCs – Towards Personalized Medicine in Oncology
    12:15 - 12:30 Q&A
    12:30 - 13:30 Coffee at the Exhibitors´ Room

    SESSION 4. Emerging Applications in Single Cell Isolation
    13:30 - 14:00 University of Jena
    Isolating single clones for CRISPR/CAS application and
    spotting beads for single cell analyses
    14:00 - 14:30 University of Rennes
    Microbiota analysis : Towards post-metagenomics and post-
    14:30 - 15:00 Suzhou Institute of Nano-Tech and Nano-Bionics
    One technology with dual uses: microarray and single cells
    analysis in mAb discovery

    Register here

  • Food allergies represent an increasingly significant health issue around the world.  Over 160 foods are known to cause allergic reactions in humans.  The U.S. Food & Drug Administration (FDA) has identified 8 food groups that are responsible for 90 percent of clinically defined (IgE-mediated) acute food allergies. 

    In this study, a lateral flow based multiplex immunoassay was developed to measure the levels of IgE (allergy) and IgG (food intolerance) in patients with known food allergies.  Food protein extracts were printed onto nitrocellulose membrane strips in an array format (LFM-lateral flow microarray). Subsequently, undiluted plasma from patients was applied and their food specific IgE and IgG profiles determined in a single conjugate pad. Various LFM formats were evaluated.

    Multiplex  & Miniaturized Lateral Flow Tests for Multianalyte Detection

    Based on traditional production technology, conventional LFAs rely on lines (control and test lines) arranged perpendicular to the flow direction. Since this design has a limitation in multiplex degree and the possibility of depletion and inadvertent interferences of assay components in multiparametric tests, there is a need for advanced array-based lateral flow assay layouts.

    SCIENION technology provides high precision and high reproducibility deposition of low volume into any surface, including nitrocellulose-based membranes. SCIENION dispensing systems, sciFLEXARRAYERs, enable miniaturization and multiplexing of classic lateral flow tests to achieve multianalyte detection.

    Here, we report on the development of LFM for the assessment of food allergy (IgE-mediated) and food intolerance (IgG-related). Food protein extracts were first deposited with sciFLEXARRAYER onto nitrocellulose membrane as an array and subsequently incorporated into a standard LF format for testing.

    Visit our booth #1579 to ge your copy

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