Apostle Inc.

3589 Nevada St
Pleasanton,  CA  94566

United States
https://www.apostlebio.com/
  • Booth: 2676

Apostle is a bio-tech company headquartered in Pleasanton, CA, aim to develop best-in-class nucleic acid isolation and preservation technologies, specifically in the fields of cfDNA for NIPT/liquid biopsy and gDNA for genomic testing and diagnosis of infectious diseases. Our technologies have been widely applied in world-class R&D studies (published on Nature Medicine, Nature Communications, Science Translational Medicine, etc.), clinical settings, and public health response and surveillance.


 Press Releases

  • MENLO PARK, Calif.Feb. 28, 2019 /PRNewswire-PRWeb/ -- Apostle Inc is pleased to announce an exclusive partnership with Beckman Coulter, a world leader in Life Sciences, for Apostle MiniMax(TM) High Efficiency Cell-Free DNA Isolation Kit. As cell-free DNA (cfDNA) workflows move beyond theoretical and into human health applications, Apostle's industry leading chemistry paired with Beckman Coulter'sportfolio of genomic reagents and liquid handling platforms enables researchers to meet the growing demands for sequencing of tumor-derived cfDNA.

    Surpassing industry standards for yield and purity of cfDNA, Apostle MiniMax(TM) technology ensures precise capture and separation of cfDNA for Liquid Biopsy. This is achieved through novel proprietary Apostle MiniMax(TM) magnetic nanoparticles with novel material composition and surface chemistry, large surface area and minimized variation. Today, at the Advances in Genome Biology and Technology (AGBT), Beckman Coulter announces this exclusive partnership with Apostle and revealed data demonstrating the outstanding performance of Apostle MiniMax(TM) High Efficiency Cell-Free DNA Isolation Kit. Due to limited cfDNA concentration, sufficient yield for next-generation sequencing (NGS) or other downstream applications can require higher volumes of plasma. As the volume increases, issues such as recovery efficiency and workflow complexity often arise. Plasma contains a host of contaminants which are problematic at this scale and can reduce assay sensitivity. Apostle MiniMax(TM) technology performs reliably across a range of volume inputs, consistently recovering high quantities of cfDNA, while effectively removing contaminants.

    "Apostle is pleased to announce a multi-year partnership agreement with Beckman CoulterBeckman Coulter has a long history as a life science industry leader, providing consumables and kit with unparalleled performance and reliability, which makes them an ideal collaborator to provide access to Apostle's innovative nucleic acid isolation products to customers around the globe. With this collaboration, customers in the liquid biopsy and DNA isolation field will have access to the best chemistry in sample processing. Beckman Coulter's established global presence, commitment to life sciences and best-in-class automation platform, combined with Apostle's top performing chemistry in isolating circulating free nucleic acids, represents a potential breakthrough for sample processing in liquid biopsy and nucleic acid isolation," said David Ge, President and CEO, Apostle Inc. 

    "Beckman Coulter is committed to working collaboratively with our customers to find the best technologies to meet their complex needs. We have listened to their ongoing challenges in working with cfDNA and sought to find ways to effectively combat those issues. This includes recognizing that an innovative product from a startup like Apostle is the best technology to address these needs," said Steve Wowk, Director of Genomics, Beckman Coulter Life Sciences.

  • Surpassing industry standards for yield and purity of cell-free DNA (cfDNA), Apostle MiniMax from Beckman Coulter is a magnetic nanoparticle–based kit that extracts cfDNA from plasma using manual or automated workflows. Due to limited cfDNA concentration, sufficient yield for NGS or other downstream applications can require higher volumes of plasma. As the volume increases, issues such as recovery efficiency and workflow complexity often arise. Plasma contains a host of contaminants that are problematic at this scale and can reduce assay sensitivity. Apostle MiniMax technology performs reliably across a range of volume inputs, consistently recovering high quantities of cfDNA while effectively removing contaminants.
    Beckman Coulter
    For info: 800-742-2345
  • San Jose, CA, April 12, 2021 - Apostle Inc is pleased to announce that the company's Apostle RNA Extraction Method is included in the recent US FNA EUA authorization of a SARS-CoV-2 Molecular Diaagnostic Test: Fulgent COVID-19 by RT-PCR Test, as reagent and system used with the FDA EUA authorized test.

    Confirmation of the final LoD was determined using serial dilutions of inactivated virus (9 copies/μL, 8 copies/μL, 7 copies/μL, 5.4 copies/μL) in 20 extracted replicates (Final LoD Study (Apostle)). The final LoD of each test was determined to be the lowest concentration resulting in positive detection in 100% of the replicates (20/20) for both targets (N1 and N2). As shown in the summary table below (Summary Final LoD Study (Apostle)), the final LoD determined for this test was 8 copies/μL.

    Source: https://www.fda.gov/media/138150/download

    “We are very glad to see more and more clinical tests are made available with the integration of the Apostle technology. We stand with our community to fight COVID-19 together.” Said Dr. David Ge, CEO of Apostle Bio.

          More information:

    • Weblink for the US FDA EUA summary of Fulgent COVID-19 by RT-PCT Test : https://www.fda.gov/media/138150/download

    • Weblink for the US FDA EUA letter of Fulgent COVID-19 by RT-PCT Test : https://www.fda.gov/media/138147/download

      About Apostle Inc

    • Apostle Inc is a biotechnology company in San Jose, CA, a provider of innovative technologies and services for public health and life sciences. Apostle aims to develop innovative technologies in the space of liquid biopsy - the sampling and analysis of non-solid biological tissue, primarily blood, often utilizing circulating free DNA (cfDNA) as a biomarker. Apostle’s innovations include Apostle MiniMax, a new scalable and automatable method to efficiently capture cfDNA from a standard blood draw; Apostle MagTouch, a nucleic acids isolation automation system, and Apostle MiniEnrich, a high-resolution DNA size enrichment technology using a magnetic nano-platform.

      In 2020, the company responded to the COVID-19 pandemic to help our community fight together with a high quality, low cost, fast, automated, Apostle COVID-19 Viral RNA Isolation System.

      More information can be found at www.apostle.bio . Contact: info@apostlebio.com


 Additional Info

We will be displaying a new product or promoting a new indication/enhanced feature for an existing product in our booth?
Yes
Included in the Export Interest Directory?
Yes
Business Needs:
Direct Sales, Distributor/Agent/Representative
Products to be exported:
MagTouch 2000, MagTouch 2000 Consumables, MiniMax cfDNA Isolation Kit, MiniMax cfDNA Blood Collection Tube, MiniMax cfDNA Preservative, MiniMax cfDNA Isolation Kit (Type S), MiniMax cfRNA Isolation Kit, MiniMax cfDNA/RNA Isolation Kit, MiniEnrich Short Fragment Enrichment Kit, MiniEnrich Carboxyl Beads, MiniGenomics UTI Isolation Kit, MiniGenomics Viral Total NA Isolation Kit, MiniGenomics Genital Tract Swab Fast Kit, MiniGenomics Stool Fast Kit (Microbe), MiniGenomics Virus Fast Kit, MiniGen
Countries of Interest
Canada, China, India, Japan, Korea (South), Singapore, United States