ACEA Biosciences, Inc.  

San Diego,  CA 
United States
https://www.aceabio.com
  • Booth: 628

ACEA Biosciences features a product line of the xCELLigence Real-Time Cell Analysis instruments as well as the NovoCyte Flow Cytometer. xCELLigence instruments allow live cell analysis that is both sensitive and reproducible. The NovoCyte aims to simplify your workflow with an affordable high performance benchtop with industry leading software.

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ACEA Biosciences features a product line of the xCELLigence Real-Time Cell Analysis instruments as well as the NovoCyte Flow Cytometer. xCELLigence instruments allow live cell analysis that is both sensitive and reproducible. The NovoCyte aims to simplify your workflow with an affordable high performance benchtop with industry leading software.


 Press Releases

  • ACEA Biosciences announced today that it has signed a definitive agreement to join Agilent Technologies, Inc. (NYSE: A).  

    ACEA Biosciences is a company known for developing highly innovative products, which are used in academia, as well as the biotech and pharmaceutical industries.  In recent years, the ACEA xCELLigence® RTCA technology has blazed a trail in immuno-oncology, pre-clinical drug discovery and development, as well as in basic academic research.  The technology is complemented by the introduction in recent years of the NovoCyte® and NovoCyte Quanteon™ portfolio of high performance bench top flow cytometry systems.

    Both ACEA and Agilent have a great reputation for scientific and technical innovation and for building systems and products of exceptional quality. As part of Agilent, ACEA will be able to leverage an unmatched global infrastructure of service and support, as well as a powerful global marketing and sales engine. Complementary engineering and scientific expertise from both companies should also provide a rich pipeline of novel systems and products well into the future.

    “The analytical instruments, systems, and software developed by ACEA, dovetail perfectly with the strategic vision and mission of Agilent Technologies,” stated Xiao Xu, Chief Executive Officer  of ACEA. “Agilent also has a number of complementary technologies, used in immuno-oncology and drug discovery, which should provide tremendous synergies.”

    “ACEA represents a unique opportunity for Agilent to expand its team and broaden its portfolio with highly complementary technology, increasing the relevance and impact we can have with our customers in the cell analysis space” said Todd Christian, Vice President & General Manager of Agilent’s Cell Analysis Division. “We share the same passion around the need for and innovation of live-cell, kinetic, and label free approaches to cell analysis extending beyond traditional end-point measurements.  Together, we will be able to offer a more comprehensive and compelling product portfolio to our collective customers.”

    “Agilent and ACEA are aligned with a common mission to provide innovative high-performance solutions that help our customers advance scientific discovery and improve healthcare,” said Xiaobo Wang, President and Chief Technology Officer (CTO) of ACEA. “We are excited for the opportunities that this unique combination will create for both our employees and our customers.”

    Agilent Technologies Inc. (NYSE: A) is headquartered in Santa Clara and is a global leader in life sciences, diagnostics, and applied chemical markets.

    About xCELLigence® Real Time Cell Analysis (RTCA) Instruments

    The xCELLigence® RTCA instruments use noninvasive biosensors to monitor and quantify cell proliferation, cell health, morphology changes, and attachment quality in a label-free, real-time manner. The xCELLigence RTCA instruments are being used in the academia, pharmaceutical, and biotech industries for applications ranging from cancer immunotherapy, cardiotoxicity, and drug discovery. To date, xCELLigence has been used in more than 1,400 publications, which can be viewed in a searchable library.

     About NovoCyte® Flow Cytometers

    The NovoCyte® and Novocyte Quanteon™ are high performance benchtop flow cytometers that are accessible to all levels of users.  With one to three different laser options and a highly customizable optical platform, the NovoCyte® can be configured for diverse applications and is readily upgradeable over time.  The NovoCyte Quanteon™ flow cytometer builds upon its wildly successful predecessor, the NovoCyte™, and provides an expanded set of capabilities that easily accommodate the large, multi-color panels found in today’s highly progressive flow cytometry laboratories. Scientists now have the flexibility to choose from 25 fluorescent channels utilizing four lasers (405, 488, 561, and 637nm) with 25 independent silicon photomultiplier (SiPM) detectors.

    About ACEA Biosciences

    Founded in 2002, ACEA Biosciences is a pioneer in the development and commercialization of high performance, cutting edge cell analysis platforms for life science research. ACEA’s xCELLigence impedance-based, label-free, real-time cell analysis instruments and NovoCyte® flow cytometers are used in pre-clinical drug discovery and development, toxicology, safety pharmacology, and basic academic research. More than 2,300 instruments have been placed globally.

    About Agilent Technologies

    Agilent Technologies Inc. (NYSE: A) is a global leader in life sciences, diagnostics, and applied chemical markets. With more than 50 years of insight and innovation, Agilent instruments, software, services, solutions, and people provide trusted answers to its customers’ most challenging questions. The company generated revenues of $4.47 billion in fiscal 2017 and employs 14,200 people worldwide. Information about Agilent is available at www.agilent.com.

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    For further information please contact:
    ACEA Biosciences, Inc.
    J. Michael Honeysett, MBA
    Vice President of Global Commercialization
    Phone: 858-299-8040
    email: mhoneysett@aceabio.com

  • We are excited to announce the release of the new 1.3.0 version of NovoExpress® software which  supports  the recently launched NovoCyte QuanteonTM flow cytometers and  NovoSampler® Q autosampler products, in addition to NovoCyte®flow cytometer and NovoSampler® Pro products.

    In addition to the functionalities supporting the expanded flow cytometer products for data acquisition, this version of NovoExpress also implements a variety of new features and functional enhancements including several highlights below:

    • New Cell Proliferation Analysis module expands the data analysis capability to model the proliferation assay data
    • Added the new Dean-Jett-Fox model, in addition to the current Watson model to enhance the data analysis capability for cell cycle assays
    • New Heat Map function enables the convenient visualization of the statistical results for multiple parameters from multiple samples
    • New Bi-variate Plot function provides a powerful tool to visualize an array of fluorescence data plotted against each other and the impact of fluorescence compensation on the results
    • Support data exporting to LIS file compatible with the Laboratory Information System (LIS)

    NovoExpress 1.3.0 is an easy-to-use and intuitive software which supports the entire NovoCyte flow cytometer product portfolio and provides powerful and professional flow cytometry data analysis functionalities. These new data analysis functions enable simplified, high-throughput single-cell multiparametric data analysis at user’s fingertips.

    Together with the recently launched 4-laser 25-color NovoCyte Quanteon flow cytometer and NovoSampler Q, ACEA Biosciences is committed to demystify Flow Cytometry and broaden its applications in curing cancer, understanding the microbiome, and safeguarding human health, etc.

    To download a free trial of the full functional NovoExpress 1.3.0 (for research use only in the United States), please click here.

  • ACEA Biosciences launches xCELLigence RTCA Software Pro, a powerful software package for running and analyzing immunotherapy experiments on the xCELLigence® Real Time Cell Analysis instruments.

    As a leading innovator in the development of tools for the cancer research laboratory, ACEA Biosciences, The Cell Analysis Company, is excited to offer xCELLigence® RTCA Software Pro, an integrated software package designed specifically for immuno-oncology applications.  Experimental design and data analysis for immune oncology researchers are now much easier, especially when combined with the high throughput and label-free xCELLigence Real Time Cell Analysis (RTCA) platforms from ACEA Biosciences

    With this new software package, scientists can automatically measure cytolysis of target tumor cells by immune effector cells and other molecules to evaluate new cancer immunotherapies. xCELLigence RTCA Software Pro is ideal for immunotherapy studies including genetically engineered CAR-T cells, antibody-dependent cell-mediated cytotoxicity (ADCC), bispecific T cell engagers (BiTes), immune checkpoint inhibitors, NK cells and much more.

    “With the promise of immunotherapies for treating cancer, the team at ACEA Biosciences wanted to develop effective software tools for this area of research.  The clinical outcome of these therapies has been remarkable in terms of patient responses,” said Aimee Chiavario, Senior Marketing Manager for Immuno-Oncology Applications at ACEA Biosciences. “We are excited to help accelerate the timelines of our immunotherapy customers.”

    Benefits of xCELLigence RTCA Software Pro include:

    • Immunotherapy experiment specific functions Users can accurately calculate % Cytolysis through the subtraction of effector background and the use of reference samples such as target tumor cells and mock effector cells. The software can also automatically determine kinetic parameters such as the time point for 50% tumor cell killing (KT50).
    • Simple experimental set up Target tumor cells, effector cells, and dose dependent treatments are easily recorded based on the experiment design and well content. The interactive software automatically recognizes control wells based on plot type selection and normalization.
    • Improved user interface With the updated 96 well plate map, target tumor cells, effector cells, or experimental drug dosages can be visualized individually or in combinations through a pie chart, enabling quick comparison between wells. Users can select and simultaneously display relevant data from specific wells. The combined plot and data analysis window provides a convenient way to demonstrate results.
    COMBINED “PLOT” AND “DATA ANALYSIS” WINDOW ENABLES A CONVENIENT WAY TO COMPARE RESULTS (ABOVE). UPDATED 96 WELL PLATE LAYOUT ALLOWS FOR SIMPLE EXPERIMENTAL SET UP (BELOW).

    About xCELLigence® Real Time Cell Analysis (RTCA)

    ACEA’s xCELLigence RTCA instruments are being used in both academia and industry for life science applications ranging from cancer immunotherapy, bacterial biofilms, vaccine development and cardiotoxicity testing. With the xCELLigence technology, scientists can non-invasively monitor the behavior of cells by quantifying cell proliferation, morphology change, and attachment quality in a label-free, real-time manner.

    About ACEA Biosciences

    Founded in 2002, ACEA Biosciences is a pioneer in the development and commercialization of high performance cell analysis platforms for life science research. ACEA’s xCELLigence® Real-Time Cell Analysis instruments and NovoCyte® aQuanteon flow cytometers are used in pre-clinical drug discovery and development, toxicology, safety pharmacology, and basic academic research. More than 2,500 instruments have been placed globally, and have been used in more than 1,800 peer-reviewed publications.

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    For further information please contact:
    ACEA Biosciences, Inc.
    Dr. Jeff Xue
    Phone: 858-299-8023
    email: jxue(at)aceabio(dot)com