Tomocube  

Daejeon,  Daejeon 
Korea (South)
https://www.tomocube.com
  • Booth: 329

Tomocube is committed to providing cutting-edge solutions in label-free 3D live cell imaging and AI-enabled analysis for the advancement of basic research, biological processes, and disease diagnosis. Our Holotomography (HT) products offer a distinctive blend of high-resolution 3D imaging, enabling the analysis of real-time subcellular dynamics, and advanced quantification capabilities for the accurate determination of volume and dry mass of individual cells and 3D tissues, without any invasive pre-treatment including fixation or molecular labeling. Tomocube provides the most versatile label-free 3D live cell analysis platform, HT-X1, with the image analysis software, TomoAnalysis.

 Press Releases

  • Boston, Massachusetts, USA — Tomocube, Inc., a leader in label-free 3D live cell imaging and AI-driven analysis, is excited to announce its participation in the ASCB|EMBO Meeting CELL BIO 2023. This premier event is scheduled from December 2 to December 6 at the Boston Convention and Exhibition Center.

    At booth #329, Tomocube, Inc. will introduce two groundbreaking innovations: the HT-X1 Holotomography Imaging System and the TomoAnalysis software suite. These cutting-edge solutions promise to revolutionize cell biology research by providing powerful tools for visualizing and analyzing cellular structures and dynamics.

    "We invite all attendees to visit booth #329 and experience the transformative potential of our HT-X1 Holotomography Imaging System and TomoAnalysis software," said Sumin Lee, Ph.D, VP of Customer Development at Tomocube, Inc. "These innovations open new frontiers in cell biology research, enabling researchers to explore the intricacies of cellular structures and dynamics."

    Product Highlights:

    HT-X1 Holotomography Imaging System: The HT-X1 is a revolutionary low-coherence holotomography imaging system that enables researchers to visualize transparent specimens in three dimensions. By generating 3D refractive index (RI) tomograms, the HT-X1 represents valuable quantitative information about cells, including volume, area, protein and lipid concentration, and dry mass. This label-free approach provides a non-invasive means of investigating cellular structures and dynamics.

    The HT-X1 has outstanding performance in the key applications of quantitative phase imaging:

    • Confluent & sensitive live cells: primary cells including stem cells, iPSC, neuronal cells, etc.
    • Monitoring of multiple samples in a multi-well imaging plate up to 96 well with stable incubation system.
    • Observing thicker samples: organoid, tissue, microfluidic device.
    • Nanomaterial delivery: better resolution without speckle noise.

    TomoAnalysis Software: Discover TomoAnalysis, the ultimate software solution for refining, segmenting, quantifying, and analyzing for Holotomography. The highlighted functions of TomoAnalysis are lipid droplet quantification, cell instance segmentation, and fluorescence-based analysis. These functions use a refractive index (RI) based thresholding method to segment masks because Holotomography image represents RI distribution. The software automatically provides quantitative information of segmented features using the characteristics of RI which is linearly proportional to concentration of biomolecules. Users can use the fluorescence signal as supplementary data using corelative fluorescence imaging with Holotomography. The software offers core Analysis pipelines and provides a range of customizable features to address diverse user needs. Researchers can refine their image data, extract meaningful measurements, and conduct in-depth quantitative analyses.

    About Tomocube, Inc.: Tomocube, Inc. is a leading company at the forefront of label-free 3D live cell imaging and AI-enabled analysis. Our mission is to advance scientific discovery by offering state-of-the-art solutions for visualizing and studying the intricate world of cells. With a commitment to innovation and excellence, Tomocube, Inc. empowers researchers and scientists to make groundbreaking contributions to the field of cell biology.

    Don't miss this opportunity to witness the future of 3D live cell imaging at ASCB|EMBO Meeting CELL BIO 2023. For more information about Tomocube, Inc. and its cutting-edge products, please visit our website at www.tomocube.com.

    Contact: Sumin Lee, Ph.D. VP of Customer Development, Tomocube, Inc. slee@tomocube.com

  • DAEJEON, South Korea – Pioneering in the field of holotomography, Tomocube Inc. proudly announces the release of its latest innovations: the TomoAnalysis™ software and the HT-ready 96 Well Plate, designed to revolutionize high-content analysis and high-throughput experiments.

    TomoAnalysis™: Unleashing the Full Potential of Holotomography

    TomoAnalysis™ represents a significant leap in the field of cellular imaging. This versatile software tool offers customizable analysis pipelines tailored to diverse research needs, enabling researchers to refine multi-modal image data, extract meaningful measurements, and perform in-depth quantitative analyses​​. Key features include 3D Visualization, Refractive Index-based Thresholding, Fluorescence Signal Segmentation, and Quantitative Measurement​​.

    TomoAnalysis™ is designed to support a wide range of applications, such as Cell Instance Segmentation, Lipid Droplet Quantification, and Fluorescence-based Analysis. Its streamlined workflow, combined with an automated batch analysis feature, significantly enhances productivity and data management efficiency​​.

    HT-ready 96 Well Plate: A New Standard for High-Content Analysis

    The HT-ready 96 Well Plate, specifically designed for use with Tomocube’s HT-X1, sets a new benchmark in high-content analysis. This innovative black 96 well plate is ideal for diverse cell culture conditions and is optimized for inverted microscopy, including holotomography, confocal microscopy, and fluorescence microscopy​​.

    Key features of the HT-ready 96 Well Plate include a stable cell culture environment, superior inner well and whole plate flatness, and zero autofluorescence for clear imaging. The plate is particularly suitable for applications such as high-throughput screening, high-resolution microscopy, real-time live cell imaging, and immunofluorescence staining​​.

    Expanding the Horizons of Cellular Research

    With the introduction of TomoAnalysis™ and the HT-ready 96 Well Plate, Tomocube Inc. continues to demonstrate its commitment to advancing scientific research and innovation. These products not only enhance the capabilities of researchers but also open new avenues for exploration in the field of cellular imaging and analysis. From Sunday to Tuesday (Dec 3-5), the Tomocube team will be at booth #329 of Cell Bio 2023 to showcase these exciting advancements in Holotomography technology. Visitors can experience firsthand how Tomocube is setting new standards in cellular imaging and analysis.

    For more information about TomoAnalysis™ and the HT-ready 96 Well Plate, please visit www.tomocube.com.

    About Tomocube Inc.

    Founded in Daejeon, South Korea, Tomocube Inc. specializes in developing cutting-edge holotomography microscopy and imaging technologies. The company's commitment to innovation and excellence has positioned it as a leader in the field, providing scientists and researchers around the world with tools to expand our understanding of the microscopic world.

    Contact: Sumin Lee, VP of Customer Development, Tomocube Inc.

    Email: slee@tomocube.com, Tel: +82-42-863-1100

 Products

  • HT-X1 Holotomography System
    Experience cutting-edge 3D visualization with Tomocube's HT-X1 Holotomography Imaging System. Capture live cell morphological and mechanical properties in high resolution, no labeling needed....

    • The Tomocube HT-X1 Holotomography Imaging System is a cutting-edge digital holotomography (HT) imaging system that enables label-free three-dimensional (3D) visualization of transparent specimens. The HT-X1 generates 3D refractive index (RI) tomograms representing the distribution of the RIs of specimens, which can then be translated into morphological, chemical, and mechanical properties. 

    The HT-X1 incorporates the high resolution, high contrast, and high sensitivity capabilities of the HT series from Tomocube and adapts them into a programmable multi-well plate imaging system with laser autofocus at a larger field of view. The HT-X1 is the first-ever holotomography technique to use a low-coherent light source with multiple beam patterns to obtain quantitative 3D RI information, thereby minimizing interference noise and eliminating the need for a calibration step for image acquisition. The motorized stage allows for tiling and multi-point analysis within each well, in addition to moving between wells. A built-in stage-top incubation system completes the live-cell imaging setup. A 3D fluorescence imaging module is incorporated to expand the information about the specimens by adding molecular information. 

     The HT-X1 has outstanding performance in the key applications of quantitative phase imaging, such as:

    • Confluent & sensitive live cells: primary cells including stem cells, iPSC, neuronal cells, etc.
    • Monitoring of multiple samples in a multi-well imaging plate
    • Observing thicker samples: organoid, tissue, microfluidic device 
    • Nanomaterial delivery: better resolution without speckle noise
  • Tomocube HT-Ready 96 Well Plate
    A black 96 well plate for high-content analysis, designed for use with Tomocube HT-X1. This plate offers versatility in cell culture, holotomography and fluorescence microscopy....

    • A black 96 well plate for high-content analysis, designed for use with Tomocube HT-X1 Holotomography system. This plate offers versatility in cell culture, holotomography and fluorescence microscopy.

    Key Features;

    • Stable cell culture environment.
    • Optimized for inverted microscopy; Holotomography (HT-X1), Confocal microscopy, Fluorescence microscopy
    • Bottom coverslip resistant to solvent for staining and fixation
    • Superior inner well and whole plate flatness
    • Zero autofluorescence for clear imaging Applications
    • Cell culture (Adhesion cells, suspension cells, and organoids)
    • High-throughput screening and high-resolution microscopy
    • Real-time live cell imaging
  • TomoAnalysis: an Image Analysis Suit for HT
    TomoAnalysis is a software that allows users to perform advanced analysis of holotomography images. With TomoAnalysis, users can visualize, segment, measure, and reconstruct HT images in 2D, 3D, and 4D....

    • TomoAnalysis provides a range of customizable procedures of analysis pipeline to address diverse user needs. Researchers can refine their multi-modal image data, extract meaningful measurements, and conduct in-depth quantitative analyses.

    Key Features;

    • 3D image visualization: It provides the best way to represent the 3D Holotomography data and users can gain a deeper understanding of the cells and organoids by volumetric visualization.
    • Refractive index-based thresholding: It provides an accurate segmentation procedure using refractive index-based thresholding.
    • Fluorescence signal segmentation: It proposes the correlative data analysis of Holotomography and Fluorescence signal. Users can use the fluorescence signal as a label to specify the region of interest and get the precise quantitative information based on Holotomography.
    • Quantitative measurement: It provides volume, surface area, projected area, concentration, dry mass, and refractive index of segmented regions.

    Applications;

    • Lipid droplet quantification: Automated segmentation and quantification, providing insights into cellular lipid content with precision and efficiency.
    • Cell Instance Segmentation: A streamlined workflow allows accurate and versatile 3D cell segmentation for quantitative measurement and monitoring.
    • Fluorescence-based Analysis: Co-visualization and correlative data analysis of Holotomography and Fluorescence signal for in-depth and multi-modal insights into subcellular contents.

Categories

Product Categories
  • Imaging
  • Laboratory Equipment
  • Microscopes
  • Microscopes Accessories
  • Software
    • Loading ...

    :
    :


    Legend
    Available Timeslot
    Scheduled Appointment
    Personal Appointments
    Appointment Request
    Blocked Timeslot
    Restricted Timeslot
    Cancelled
    Declined