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Mashup Score: 0Doxycycline protects against sepsis-induced endothelial glycocalyx shedding - 50 minute(s) ago
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Mashup Score: 0LGBTQ+ foster youths could expect different experiences as Tennessee and Colorado pass opposing laws - 51 minute(s) ago
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In Tennessee, the Republican supermajority passed a measure that would allow LGBTQ+ children to be placed with families that hold anti-LGBTQ+ beliefs. Meanwhile, Colorado’s Democratic majority passed a bill to install protections for children in such placements. So much for "love thy neighbor" and "all children deserve a loving home." #hypocriticallegislation #protectLGBTQ+youths
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Zach Klaassen and Zach Reardon delve into the nuances of managing nonmetastatic castration-resistant prostate cancer (nmCRPC) in clinical practice. Dr. Reardon discusses the evolving landscape of nmCRPC treatment, emphasizing the significance of early detection and the impact of advancing imaging technologies like PSMA PET scans on patient categorization. He advocates for treating patients with…
Source: www.urotoday.comCategories: General Medicine News, General NewsTweet
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RF infusion on pain intensity and areas of hyperalgesia and allodynia in healthy volunteers. Nine studies were included. The intervention treatment consisted in RF infusion that was compared with placebo (saline solution). The primary outcome was pain intensity assessment at 30 ± 15 minutes after RF or placebo discontinuation, assessed by any pain scale and using any quantitative sensory testing. Moreover, postwithdrawal pain scores were compared with baseline scores in each treatment. Secondary outcomes included the areas (% of basal values) of hyperalgesia and allodynia. Subjects during RF treatment reported higher pain scores after discontinuation than during treatment with placebo [standardized mean difference (SMD): 0.50, 95% confidence interval (CI): 0.03-0.97; P = 0.04, I2 = 71%]. A significant decrease in pain scores, compared with baseline values, was found in the placebo treatment (SMD: −0.87, 95% CI: −1.61 to −0.13; P = 0.02, I2 = 87%), but not in the RF treatment (SMD: −0.2
Source: journals.lww.comCategories: General Medicine News, RheumatologyTweet
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c prescription, including opioids, at 3 and 6 months postsurgery for patients with and without preoperative sarcopenia, and to determine the impact of sarcopenia on analgesic use after neuraxial anesthesia surgery. Methods: Patients undergoing surgery under neuraxial anesthesia were categorized into sarcopenic and nonsarcopenic groups based on preoperative diagnosis using the ICD-10-CM code M62.84. Propensity score matching in a 1:4 ratio was applied for group matching. Analgesic prescription rates were evaluated at 3 and 6 months postsurgery, and multivariable logistic regression was used to analyze analgesic use, comparing patients with and without preoperative sarcopenia. Results: Among 3805 surgical patients, 761 had sarcopenia, while 3044 did not. At 3 months postsurgery, 62.3% of sarcopenic patients received analgesics, with 2.9% receiving opioids, compared to 57.1% of nonsarcopenic patients receiving analgesics and 0.8% receiving opioids. At 6 months postsurgery, 30.8% of sarcop
Source: journals.lww.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0Amgen CEO Bob Bradway's 2023 Letter to Shareholders - 1 hour(s) ago
Amgen performed well in 2023, serving millions of patients around the world with our innovative, life-changing medicines; advancing many promising new first-in-class molecules in our pipeline; completing a significant acquisition that establishes us as a leader in treating rare diseases; and delivering strong financial performance.
Source: wwwext.amgen.comCategories: General Medicine News, PayerTweet
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Mashup Score: 0HLTH Europe 2024 | Amsterdam | 17 - 20 June - 1 hour(s) ago
The US’s #1 healthcare event is coming to Europe. From 17-20 June 2024, HLTH Europe will unite the entire European ecosystem in Amsterdam.
Source: europe.hlth.comCategories: General Medicine News, General HCPsTweet
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The meta-analysis demonstrated gout with high blood uric acid levels significantly increases the risk of experiencing angina attacks.
Source: www.hcplive.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0The Human Intracerebral EEG Platform and the power of big data: Dr. Philippe Ryvlin // International League Against Epilepsy - 1 hour(s) ago
Epigraph Vol. 26 Issue 2, Spring 2024 Cite this article: Nouri M. The Human Intracerebral EEG Platform and the power of big data: Dr. Philippe Ryvlin. Epigraph 2024; 26(2):62-68. The Human Intracerebral EEG Platform is a cloud-based, collaborative environment that encourages centers to share data and conduct research with state-of-the-art methodologies and software. Dr. Maryam Nouri interviews Dr. Philippe Ryvlin about the potential of the platform to advance the understanding of human brain function.
Source: www.ilae.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 67
Gas stoves spew nitrogen dioxide at levels that frequently exceed those that are deemed safe by health organizations
Source: www.scientificamerican.comCategories: General Medicine News, Infectious DiseaseTweet
These findings suggest that doxycycline protects against LPS-induced eGC shedding, and it could reduce vascular hyperpermeability, neutrophils transmigration, and microvascular impairment.