Progenesis  

La Jolla,  CA 
United States
http://www.progenesis.com
  • Booth: 1713

Driven by science and innovation, Progenesis has become the new leader of preimplantation genetic testing to help build healthy families. Our portal design and function is the product of the best minds in the IVF industry, helping to optimize clinics' genetic testing workflow. Our success lies in our passionate team, dedicated to providing the best quality testing and customer care. Phone: (858) 257-2122 Email: info@progenesis.com


 Products

  • Previda
    Previda® is a Pre-implantation genetic test for Aneuploidies (PGT-A) formerly known as Pre-implantation genetic screening or PGS. PGT-A is intended for couples who are undergoing treatment to become pregnant (In-vitro Fertilization-IVF)....

  • Previda® is a Pre-implantation genetic test for Aneuploidies (PGT-A) formerly known as Pre-implantation genetic screening or PGS. PGT-A is intended for couples who are undergoing treatment to become pregnant (In-vitro Fertilization-IVF). The best assess the genetic health of the embryo through chromosomal screening, assessing the lack or excess in the normal set (Aneuploidy). Aneuploidies are the common cause of miscarriages and can result in the birth of the child with a chromosomal disease.

    We used in Previda® Next-generation sequencing (NGS) combined with bioinformatics algorithms to count the number of copies of chromosomes with maximum accuracy and precision.

    The results provide important information about the chromosomal health of the embryo before implantation , the possible results being: Euploidy, Aneuploidy or Mosaic.

    Your doctor and IVF Clinic staff can utilize this information by choosing the embryo for transfer that will increase your chance of successful pregnancy, thus bringing you closer to your dream of having a healthy baby.

    Request more information about our test and services, it is important to also talk to your doctor about Genetic tests available during IVF treatment.

  • Previda-Dx/SR
    Previda®-DX Pre-implantation genetic testing for monogenic or single gene disorders (PGT-M) is a reproductive technology used to diagnose genetic disorders in embryos before they are implanted into the uterus during in vitro fertilization (IVF)....

  • Previda®-DX Pre-implantation genetic testing for monogenic or single gene disorders (PGT-M) is a reproductive technology used to diagnose genetic disorders in embryos before they are implanted into the uterus during in vitro fertilization (IVF). This testing allows couples who are carriers of a specific genetic disorder to reduce the risk of passing it on to their offspring.

    Previda®-DX PGT-M particularly beneficial for individuals or couples who have a known family history of a monogenic disorder or carry genetic mutations that increase the risk of having a child with a specific genetic condition. Some examples of monogenic disorders that can be screened for include cystic fibrosis, sickle cell anemia, Huntington's disease, and thalassemia.

    The process of Previda®-DX PGT-M involves several steps:

    1.Pre-PGT Work Up:- The Genetic work-up in Couple.
    Find out the Variants or mutations in affected family members or Additional Family members testing.

    2. IVF procedure: The woman's eggs are retrieved and fertilized with the sperm in a laboratory to create embryos.

    3. Embryo biopsy: On the 3rd day/5th day of embryo development, when the embryo consists of about 6-8 cells in Blastomere/ mature blastocyst have 200-300 cells.
    one cell in Blastomere biopsy / five or six cell in blastocyst are removed for genetic analysis.(Now most of the IVF Centre go for Blastocyst Biopsy or Trophectoderm Biopsy (TE) Biospy).

    4. Genetic analysis: The extracted cells are analyzed using various techniques to identify the presence or absence of the specific genetic mutation associated with the targeted disorder.

    5. Embryo selection: Only unaffected embryos (without the genetic mutation) are considered for transfer into the woman's uterus. This reduces the chances of having a child affected by the monogenic disorder.

    6. Embryo transfer: The selected and tested embryos are transferred to the uterus for potential implantation and development.

    Previda®-DX PGT-M can increase the chances of having a healthy baby and reduce the burden of genetic diseases within families. However, it is important to note that this testing only screens for specific single gene disorders and does not address other genetic conditions or complex disorders.

    It is recommended that individuals or couples considering Previda®-DX PGT-M consult with a genetic counselor or reproductive specialist to discuss the suitability, limitations, potential risks, and ethics associated with this procedure.
  • MitoSure
    MitoSure® is a test performed on embryos that measures levels of mitochondrial DNA (mtDNA). Large amounts of mtDNA may be an indicator of developmental delay and implantation failure....

  • MitoSure® provides an estimate of the amount of mitochondrial DNA present in an embryo relative to nuclear DNA. An abnormally high MitoSure® score (above 2) may be indicative of developmental delay. When selecting viable embryos for implantation, MitoSure® may be of use as a novel biomarker for the deselection of unfit embryos.