Itasca,  IL 
United States
  • Booth: 768

Booth Profile

Biosynth Carbosynth is the new global brand created from the merger of two key players in the fine chemicals market. We manufacture and source a vast range of chemical and biochemical products and specialise in carbohydrates, nucleosides, antimicrobials, APIs, enzyme substrates and natural products. Custom synthesis is a one of the pillars of our business. We have top industry expertise in enzyme substrates, building blocks for organic synthesis as well as carbohydrate and nucleoside chemistry. In addition, quality is our top priority and we operate according to the ISO and GMP quality standards. -- Visit us to learn more about the revolutionary AquaSpark™ probes! -- Biosynth Carbosynth's own biology and chemistry labs constantly drive the further development of molecules for the most sensitive detection methods in immuno assays and microbiology. In recent years Biosynth Carbosynth has successfully introduced innovative fluorogenic and luminescence-based systems into the field.



 Press Releases

  • Ultrasensitive detection of Salmonella and Listeria monocytogenes

    Researchers from the Tel Aviv University, Nemis Technologies and Biosynth Carbosynth recently reported the new AquaSpark™-based chemiluminescence probes for the ultrasensitive direct detection of viable pathogenic bacteria. This study demonstrated that the enzyme substrates could detect their corresponding bacteria with an LOD value about 600‐fold lower than that of fluorescent probes. The authors were able to detect a minimum of 10 Salmonella cells within only 6 hours incubation. Both speed and sensitivity are critical attributes of probes for the development of urgently needed detection systems for point-of-care diagnostics.  

    Reference: Roth‐Konforti, M. , Green, O. , Hupfeld, M. , Fieseler, L. , Heinrich, N. , Ihssen, J. , Vorberg, R. , Wick, L. , Spitz, U. and Shabat, D. (2019), Ultrasensitive Detection of Salmonella and Listeria monocytogenes by Small‐Molecule Chemiluminescence Probes. Angew. Chem. Int. Ed.. doi:10.1002/anie.201904719

    About AquaSpark™:

    Researchers from Tel Aviv University developed new reagents termed 'AquaSpark' to visually detect processes inside cells or biological samples. In contrast to luciferin or fluorescent probes, the new compounds do not require any genetic modification of cells and no excitation light source is needed. Biosynth Carbosynth received the license to manufacture the pioneering compounds and to market them in the diagnostics field.

    About Biosynth Carbosynth:

    Biosynth Carbosynth is the new global brand created from the merger of two key players in the fine chemicals market. The company  manufactures and sources a vast range of chemical and biochemical products and specialises in carbohydrates, nucleosides, antimicrobials, APIs, enzyme substrates, natural products, and chemiluminescence-based probes. Biosynth Carbosynth and TAU are constantly developing new AquaSpark™ probes in close collaboration and are expanding the unique product range.

    Biosynth Carbosynth

    About Nemis:

    Incorporated in January 2018, Nemis Technologies AG is a joint-venture between Biosynth and RAMOT, the Tel Aviv University business Engagement Center established to develop rapid and innovative diagnostic test kits based on the AquaSparktechnology jointly developed and owned by Biosynth and Ramot.

    To learn more visit us at AACC, Anaheim, stand #768!


  • AquaSpark™ Chemiluminescence Probes and Substrates
    The AquaSpark™ family of products comprises a range of chemiluminescence probes and enzyme substrates for research and diagnostic applications. They can be used to detect a large number of enzyme activities, bio-markers, metabolites, or pathogens. For example: Phosphatase (AP), Peroxidase (HRP), Hydrogen Peroxide, beta-Galactosidase, NAHD. ...

  • AquaSpark™ Alkaline Phosphatase (AP) Substrate

    Trim your assays setup in the most cost-efficient way using a dedicated AP substrate.

    The AquaSpark™ AP substrates do not require enhancers or additional luminescence dyes. No phenolic enhancer, oxidant and co-factors are needed, as it is the case for luminol-based procedures. AquaSpark™ offers the highest signal intensity combined with excellent signal-to-background ratio.

    AquaSpark™ Enhanced HRP Detection Solution

    The first Dioxetan-based substrate for the detection of horseradish peroxidase (HRP) conjugates in enzyme-linked immunosorbent assays (ELISA). The ready-to-use detection solution contains hydrogen peroxide (H2O2 ).

    Discover all AquaSpark™ chemiluminescent enzyme substrates and probes

 Additional Info

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