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Celiac disease is a human enteropathy caused by a permanent intolerance to gluten and more specifically to its protein fraction called gliadin. The ingestion of this protein induces, in genetically predisposed individuals, a severe lesion of the intestinal mucosa characterised histologically by crypt hyperplasia with total or subtotal atrophy of the intestinal villi.
Due to the lack of a common symptomatology to facilitate diagnosis, as well as the high number of asymptomatic cases with intestinal deterioration, 85% of people with celiac disease are unaware of their gluten intolerance. This could lead to multiple and quite serious diseases, so the importance of early detection is vital to avoid major problems and allow the intestine to regenerate.
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